Monday, July 21, 2014

14 weeks tomorrow

MaterniT21 results are in!

Negative for everything.  So, neither baby has a genetic abnormality.  Whew!  What a relief.

Next step, the level 2 ultrasound.  We'll do that as soon as we can at 18 weeks.  They stated if they couldn't see everything, we may have to come back at 22 weeks.  That's fine with me!

Ultrasound date is 8/19/14.

Thursday, July 10, 2014

12 weeks

Yes, yes. I haven't updated in a while. Things are crazy. As of Monday, both beans were still alive and measuring 6 days ahead. Woohoo!!!! Heartbeats were 175 and 160. There's been a lot of scares along the way. Too many to list here. We should get the MaterniT21 results in the next 2 weeks and then the biggest obstacle is the 20 week anatomy scan. I think if we get through both of those, I just might start believing. 

So, here they are: 
A:
 
 
And B:  

 

Tuesday, June 10, 2014

Second Ultrasound

The second ultrasound on Monday, June 9, 2014 at 7w6d shows: 

2 heartbeats at 177 and 178 measuring 8w1d and 7w6d.  (17.6 mm and 15.7 mm)

Whew! 


Next ultrasound at 9w3d on Friday, June 20th. 

Thursday, May 29, 2014

First Ultrasound


Thursday, May 29, 2014 Ultrasound

6 weeks 2 days

And, the results are: 

2 heartbeats.  Each in their own gestational sacs.  Whew!  Measuring perfectly at 6w2d and 6w1d and heartbeats are 121 and 120. 

There might have been a third gestational sac that never really formed.  It's hard to tell and it really doesn't matter.  But, it would explain the wonky betas.  Let's hope that's it. 

We have a long race ahead of us, but it's a very good start. 

Without further ado, here's the pictures: 


 
I can't figure out how to turn this one, but either way, they're the same picture. 
 
Next ultrasound will be Monday, June 9th.  We'll be 7w 6d. 

Thursday, May 8, 2014

IVF #4 The POAS Journey

Wednesday, May 7, 2014 - 8 days past retrieval (DPO) and 3 days past 5 day transfer (3dp5dt):
In the past I've had lingering trigger on this day and the next, so a + might mean nothing. 

It look pretty negative to me.  There might be the faintest hint of a shadow. 
But, that's probably the trigger. 



 Thursday, May 8, 2014 - 9 DPO and 4dp5dt: 
Is that the faintest hint of a +?  Can you see it?  It could still be the trigger.  I've been fooled by the trigger before.  Tomorrow will tell. 





Friday, May 9, 2014 - 10 DPO and 5dp5dt: 
Hhhmmm.  Well, that's a line. 


 Saturday, May 10, 2014 - 11 DPO and 6dp5dt:
That's definitely a darker line. 


 Sunday, May 11, 2014 - 12  DPO and 7dp5dt: 
THAT is a gorgeous line!


Monday, May 12, 2014 - 13 DPO and 8dp5dt:  Didn't test. 


Tuesday, May 13, 2014 - 14 DPO and 8dp5dt:
It's starting to make the control line light.  Beta today.  I'm guessing it'll be between 300-400. 


And the beta is.........


385.  (I'll pat myself on the back a little for the correct guess and being able to read HPTs.  :)  )

Progesterone at 97. 


And the second beta at 16 DPO will be great, too, right?
No. It's not. Because life is never easy for me like that.
The second beta is 662.
Let me do the math for you. That's a 61 hour doubling time, which, of course, sucks.

I know, I know, vanishing twin/triplet, anything could be going on, blah, blah, blah.
But, really, we're done. No more betas, no super early ultrasound. We'll be doing an ultrasound on Thursday, May 29, 2014 at 6w2d. Either there will be a heartbeat or there won't. I'll let you know.

Thursday, May 1, 2014

IVF #4 Results

13 eggs retrieved

Day 1: April 30, 2014: 10 were mature and 9 fertilized!!! That's my best response yet!


Day 2: May 1, 2014: All 9 still growing. 8 are 4 cell (right where they're supposed to be) and 1 is a 3 cell. We decided we're going to PGS them and include the 7 frozen since we're going to do it anyways. I hope this is the right decision.


Day 3: May 2, 2014: Feeling more discouraged today. :( They are supposed to be 8 cell today. 6 are 8 cell, BUT 3 of those are experiencing 10-15% fragmentation. One is a perfect 6 cell. (This doesn't worry me. I've had 3 6 cellers on day 3 before and they all made it to blast.) The other 2 are a 4 cell and a 5 cell, both fragmented. Those 2 have probably arrested. We finished the consent paperwork and our own bloodtests for the PGS stuff. We'll see how it goes tomorrow. If there are 1 or 2 that look great, we'll transfer them on day 5. If everyone's looking like they'll blast on day 6, we'll biopsy and freeze everything. Stand by to stand by....


Day 4: May 3, 2014: So, OK today. I found out they cultured them separately, so we know who has done what.
2 of the 8 cell-ers from yesterday are fully compacted morulas today. (This is just where they should be.)
2 of the 8 cell-ers from yesterday are 12 cell-ers today with no fragmentation. That's ok. I've had them at 12 cell before and they've made it to blast by day 6.
2 of them are 10 cell-ers. One of them was the 5 cell from yesterday! I'm surprised he turned it around! He has a little fragmentation, but otherwise looks good. What a fighter! The other 10 cell-er was an 8 cell from yesterday.
There's an 8 cell and a 6 cell from yesterday that are an 8 cell and a 6 cell today. That's a bad sign. Too bad about them. I had high hopes for them. :(
The last one is the four cell that was a four cell yesterday and probably a 4 cell the day before. This one's basically out of the running.

So, the plan is to see if 1 or 2 of the morulas are good looking blasts tomorrow and look ready to transfer. If so, we'll transfer at 9 am. If not we'll do no transfer this cycle. We'll just hope as many make it blast as possible and we can biopsy and freeze them.


Day 5: Here we are! So the 2 morulas from yesterday formed a perfect AA hatching blast and a 2cc blast. (We'll talk about the 2cc in a second.) One of the 12 cell-ers from yesterday jumped ahead and made a beautiful AA early blast.

Those 3 were transferred this morning.

The others are now 2 compacted morulas and 2 half compacted morulas. The 2 half compacted morulas don't look that good, so we'll see how they look tomorrow. One of them is the 5 cell to 10 cell from yesterday and the day before. :( Come on little fighter!

So about that 2cc....... They didn't want to transfer it. I insisted. When I looked at it with the embryologist she said that the ICM was actually really well formed, but the trophectoderm was degenerating. So would that make it a 2ac? I looked at some studies and feel really good about the decision to transfer it.

So, without further ado.  Here are the pictures I have: 

The one on the bottom left is the "2CC".  The top one is the top one below and the bottom right one is the bottom one below. 

This is the top one in the picture above.  It was an early blast rated AA in the morning, but really started to expand and by transfer it looks like it's hatching at the one o'clock in the above picture. 

This one is the 2AA in the morning.  It is definitely hatching at transfer which you can see in the top 2 pictures at between the 6 and 7 o'clock.  See that little bit sticking out?  That's the beginning of hatching. 



Day 6:  The embryologist called and stated none had made it to freeze.  Very angry about this.  She said they had made it to blast, but were 2CC and therefore not good enough to freeze.  I don't know if this speaks to an excellent quality for the 2 good ones and for an excellent quality of our frosties or what.  Hindsight being 20/20, I would have transferred the 2 morulas and the runt from above and vitrified and tested the 2 excellent ones with our frozen 7.  I think that would've given the most number of embryos a chance.  Or, I wish I had thought of really forcing the issue to freeze the bad ones.  If they don't survive the thaw, then so be it. At least they would've had a chance....  :(

Oh well, there's many things I would've done differently in this TTC #3 journey.  (Especially started sooner!)  But, all we can do is move forward and do the best we can. 

Friday, April 11, 2014

IVF #4 Day by day.

BCPs started March 28th with my period.  Last BCP April 10th.  Baseline on April 11th, everything is quiet and the lining is thin.   

Saturday, April 12, 2014 - CD 1 - Period starts

Sunday, April 13 - CD 2 - Microdose Lupron 10 units AM & PM

Monday, April 14 - CD 3 - Microdose Lupron 10 units AM & PM

Tuesday, April 15 - CD  4 - Microdose Lupron 10 units AM & PM, 2.5 mg Letrozole in the AM, 225 Follistim, 225 Menopur, .3cc Saizen, .5mg Dexamethasone in the PM

Wednesday, April 16 - CD 5 - Microdose Lupron 10 units AM & PM, 2.5 mg Letrozole in the AM, 225 Follistim, 225 Menopur, .3cc Saizen, .5mg Dexamethasone in the PM

Thursday, April 17 - CD 6 - Microdose Lupron 10 units AM & PM, 2.5 mg Letrozole in the AM, 225 Follistim, 225 Menopur, .3cc Saizen, .5mg Dexamethasone in the PM

Friday, April 18 - CD 7 - Microdose Lupron 10 units AM & PM, 2.5 mg Letrozole in the AM, 225 Follistim, 375 Menopur, .3cc Saizen, .5mg Dexamethasone in the PM 

         Ultrasound and Bloodwork - Quiet.  12 follicles all less than 10
         E2=65, P4=0.473, LH = 5.06
         They upped my Follistim to 375 because my E2 was so low. 

Saturday, April 19 - CD 8 - Microdose Lupron 10 units AM & PM, 2.5 mg Letrozole in the AM, 375 Follistim, 225 Menopur, .3cc Saizen, .5mg Dexamethasone in the PM

Sunday, April 20 - CD 9 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM

Monday, April 21 - CD 10 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM 

          Ultrasound and Bloodwork - 14 total follicles, but one was large at 16 :( 
          All the rest 10 and under. 
          E2 = 145, P4 = 0.379, LH = 2.58

Tuesday, April 22 - CD 11 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM 

Wednesday, April 23 - CD 12 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM

Thursday, April 24 - CD 13 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM

          Ultrasound and Bloodwork - 16 total follicles!!!  Lining at 11. 
          The biggest are: 16, 15, 14, 14, 13, 12, 12, 11, 10, 9
          E2 = 502, P4 = 0.418, LH = 1.8

Friday, April 25 - CD 14 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM 

          Ultrasound and Bloodwork - Still growing.  Lining still looks good
          They are: 19.5, 16.5, 16, 15, 14.5, 12.5, 12, 12, 11, 9
           E2 = 775, P4 = 0.6

Saturday, April 26 - CD 15 - Microdose Lupron 10 units AM & PM, 375 Follistim, 225 Menopur, .5mg Dexamethasone in the PM 

          Ultrasound and Bloodwork - Still growing.  Lining still looks good
          They are: 18.5, 17, 16, 15.5, 15, 14.5, 14, 13, 13, 13, 12.5, 11.5, 10.5, 9.5, 8.5
           E2 = 1030

Sunday, April 27 - CD 16 - Microdose Lupron 10 units AM, 375 Follistim, 10,000 iu Trigger

          Ultrasound and Bloodwork - Still growing.  Lining still looks good
          They are: 22.5, 21.5, 18.5, 18.5, 16.5, 15.5, 15.5, 15, 13.5, 13, 12.5, 12, 11
           E2 = 1295, P4 = 0.7

Monday, April 28 - CD 17 - I tested my FMU in the AM and it was very barely positive. This worried me, so I decided to take a 5000 iu Booster Trigger and also 100 Follistim and 150 Menopur

Tuesday, April 29 - CD 18 - Retrieval Day: 13 Eggs!